10 Things Dogs Can Smell That Humans Cannot

Oct 1, 2025byEmily Dawson

Dogs experience the world through scent in ways that are far beyond human ability. With hundreds of millions of olfactory receptors compared to our few million, their noses can detect odours at concentrations so faint we would never notice them.

This means dogs are not only aware of everyday smells we overlook, but they can also pick up on subtle changes in people, animals, and the environment.

This article is for general knowledge only and is based on information from online sources. Dogs’ abilities can vary by breed, training, and environment.

1. Cancer Cells

Cancer Cells
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Medical research confirms that dogs have the ability to detect certain cancers through smell alone. Their sensitive noses pick up on volatile organic compounds that cancer cells release into the body.

These microscopic scent signatures are completely undetectable to humans. Studies show trained dogs identifying lung, breast, and bladder cancers with accuracy rates as high as 97% by sniffing samples.

What makes this ability remarkable is that dogs often detect these cancers in early stages, before conventional medical tests can find them. This natural talent has led to specialized cancer-detection training programs where dogs help screen patients non-invasively.

2. Dangerous Blood Sugar Levels

Dangerous Blood Sugar Levels
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When blood sugar levels plummet in a diabetic person, their body chemistry changes in ways too subtle for humans to detect, but not for dogs.

Trained diabetic alert dogs notice the rise of isoprene in their owner’s breath during hypoglycemic episodes. They respond by nudging, pawing, or otherwise alerting their person before symptoms become severe.

Many diabetics report their alert dogs wake them from sleep when blood sugar drops dangerously low at night. This remarkable ability has transformed countless lives, giving diabetics greater independence and peace of mind through their four-legged early warning system.

3. Seizures Before They Happen

Seizures Before They Happen
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The mysterious ability of some dogs to predict seizures has baffled scientists for years. These remarkable canines show distinct behavioral changes like pacing, whining, or nuzzling their owners, minutes to hours before a seizure occurs.

Research suggests they detect subtle scent changes produced by shifts in brain chemistry preceding epileptic episodes.

While humans remain unaware of these invisible warning signs, a trained seizure-response dog might gently guide their person to safety or position themselves to prevent injury during a fall. This natural ability offers epilepsy patients precious preparation time they wouldn’t otherwise have.

4. Buried Human Remains

Buried Human Remains
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Cadaver dogs possess an almost supernatural talent for locating human remains, even when buried deep underground or submerged in water for years.

Their noses detect the specific chemical compounds released during decomposition, putrescine and cadaverine, at concentrations as low as one part per trillion. This sensitivity allows them to find remains in scenarios that would defeat even sophisticated electronic equipment.

Search and rescue teams rely on these specialized dogs to locate victims after disasters or help solve cold cases. The dogs can differentiate human remains from animal remains and work effectively across challenging terrain, making them invaluable assets in recovery operations that would otherwise seem impossible.

5. Fear And Anxiety

Fear And Anxiety
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The saying that dogs can “smell fear” isn’t just a figure of speech, it’s scientific fact. When humans experience fear or anxiety, our bodies release stress hormones like adrenaline and cortisol that subtly alter our scent.

Dogs detect these chemical signals instantly, explaining why they often react to our emotional states before we’ve shown any obvious signs. Research confirms dogs can distinguish between samples of human sweat taken during states of fear versus calm.

This ability makes dogs particularly valuable as support animals for people with anxiety disorders or PTSD. They often alert their handlers to rising stress levels before a full panic attack develops, creating opportunities for early intervention techniques.

6. Early Pregnancy

Early Pregnancy
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Many women report their dogs behaving differently toward them during early pregnancy, sometimes before they even know they’re expecting. This isn’t coincidence but another example of canine scent detection at work.

Hormonal shifts during pregnancy, particularly increases in estrogen, hCG, and progesterone, create subtle changes in a woman’s scent profile. Dogs notice these shifts immediately, often becoming more protective or attentive around pregnant owners.

Some dogs will begin to follow their pregnant owners everywhere or rest their heads against the woman’s abdomen. While there aren’t many formal studies on this phenomenon, veterinarians and dog trainers widely acknowledge this natural ability based on countless consistent reports.

7. Impending Natural Disasters

Impending Natural Disasters
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Before earthquakes or severe storms hit, some dogs display unusual anxiety or refuse to enter buildings. What explains this seemingly psychic behavior? Their superior sense of smell.

Scientists believe dogs detect subtle environmental changes humans miss completely. They may smell released gases from shifting earth before earthquakes or detect the ionization of air molecules preceding lightning storms.

Historical records document this phenomenon for centuries, with numerous accounts of dogs behaving strangely before major earthquakes. In 1975, officials in Haicheng, China even ordered an evacuation based partly on unusual animal behavior, including dogs, potentially saving thousands when a 7.3 magnitude earthquake struck. Their natural early warning system works when our technology sometimes cannot.

8. Certain Infectious Diseases

Certain Infectious Diseases
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The COVID-19 pandemic revealed another remarkable canine talent: dogs can smell viral infections. Trained detection dogs identified COVID-positive individuals with accuracy rates exceeding 90% in multiple studies.

They accomplish this by detecting metabolic changes that occur when the body fights infection. These changes create unique volatile organic compound patterns in breath, sweat, and urine, patterns invisible to humans but obvious to dogs.

This ability extends beyond COVID. Research shows dogs can detect malaria, C. difficile bacterial infections, and other diseases through scent alone. Their incredible sensitivity could revolutionize disease screening in places lacking advanced medical facilities, potentially saving countless lives through early, non-invasive detection.

9. Electronic Storage Devices

Electronic Storage Devices
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Law enforcement agencies have a secret weapon for finding hidden digital evidence: dogs trained to sniff out electronic storage devices.

These specialized K-9s can locate USB drives, SD cards, and hard drives concealed in walls, furniture, or clothing. They detect triphenylphosphine oxide (TPPO), a chemical compound used in manufacturing electronic components that humans cannot smell.

Electronic storage detection dogs have proven crucial in cases involving crimes where digital evidence was deliberately hidden. One famous example is Bear, a black Labrador whose nose helped authorities locate crucial digital evidence in the Jared Fogle case. These remarkable dogs find tiny memory cards that human searchers would likely miss completely.

10. Bedbugs And Other Pests

Bedbugs And Other Pests
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Professional bedbug detection dogs locate these elusive pests with astonishing 95-98% accuracy, finding infestations humans would completely miss.

These specialized canines detect the pheromones bedbugs release at concentrations as low as one part per trillion. They can pinpoint a single bedbug or egg hidden in a mattress seam, wall outlet, or picture frame in minutes, a task that might take human inspectors hours with less reliable results.

Pest control companies increasingly rely on these dogs for early detection, allowing for targeted treatment before infestations spread. Similar training enables dogs to locate termites inside walls or carpenter ants in building foundations, making them valuable tools in property protection and pest management.

Emily Dawson
byEmily Dawson

Toronto-based freelance writer and lifelong cat lover. Emily covers pet care, animal behavior, and heartwarming rescue stories. She has adopted three shelter cats and actively supports local animal charities.